Air pollution has been estimated to lead to ca. 10.000 premature deaths every year in the Nordic countries. The external costs related to the health effects of air pollution amounts to EUR 8-13 billion per year. Main drivers, such as changes in climate, anthropogenic emissions, building structure and demography have a vast impact on air quality-related effects on human health. The purpose of the FutureAirNordic project has been to investigate how potential future changes in main drivers will impact the assessment of air quality-related human health effects. Estimations of premature mortality due to exposure to air pollution as well as the external costs associated with the negative health effects have been analyzed. The results can contribute to improved assessments under future conditions and can be used to evaluate how policies and regulations impact the health effects of air pollution.